Tetsuro Yoshimaru Selected Research

Brefeldin A

10/2021	The survival and proliferation of osteosarcoma cells are dependent on the mitochondrial BIG3-PHB2 complex formation.
9/2021	Functional genomics for breast cancer drug target discovery.
10/2019	Biophysical characterization of the breast cancer-related BIG3-PHB2 interaction: Effect of non-conserved loop region of BIG3 on the structure and the interaction.
12/2017	Stapled BIG3 helical peptide ERAP potentiates anti-tumour activity for breast cancer therapeutics.
1/2015	BIG3 Inhibits the Estrogen-Dependent Nuclear Translocation of PHB2 via Multiple Karyopherin-Alpha Proteins in Breast Cancer Cells.
7/2014	Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (BIG3) is predicted to interact with its partner through an ARM-type α-helical structure.

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Tetsuro Yoshimaru Research Topics

Disease

13	Breast Neoplasms (Breast Cancer) 10/2021 - 01/2013
8	Neoplasms (Cancer) 09/2021 - 02/2014
3	Neoplasm Metastasis (Metastasis) 09/2021 - 05/2012
3	Hypersensitivity (Allergy) 04/2009 - 01/2005
2	Carcinogenesis 02/2020 - 02/2013
2	Leukemia 10/2008 - 10/2002
1	Osteosarcoma (Osteogenic Sarcoma) 10/2021
1	Triple Negative Breast Neoplasms 05/2018
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2018
1	Microcephaly 02/2013
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2012
1	Necrosis 07/2009
1	Mycoses (Diseases, Fungus) 01/2006
1	Infections 01/2006

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 10/2021 - 07/2014
6	Guanine NucleotidesIBA 10/2021 - 07/2014
6	Brefeldin AIBA 10/2021 - 07/2014
5	Estrogens (Estrogen)FDA Link 10/2021 - 07/2014
5	Pharmaceutical PreparationsIBA 09/2021 - 04/2009
5	Peptides (Polypeptides)IBA 02/2020 - 01/2013
3	Small Interfering RNA (siRNA)IBA 02/2020 - 02/2014
3	Tamoxifen FDA LinkGeneric 12/2017 - 01/2013
3	Phenobarbital (Luminal)FDA Link 12/2017 - 01/2013
2	Epidermal Growth Factor (EGF)IBA 05/2018 - 05/2015
2	xanthohumolIBA 04/2017 - 12/2014
2	ProhibitinsIBA 01/2015 - 12/2014
2	SilverIBA 06/2006 - 10/2002
2	Heavy MetalsIBA 06/2006 - 01/2005
1	ErbB Receptors (EGF Receptor)IBA 09/2021
1	Phosphotransferases (Kinase)IBA 09/2021
1	Protein Kinases (Protein Kinase)IBA 09/2021
1	Carrier Proteins (Binding Protein)IBA 02/2020
1	Biomarkers (Surrogate Marker)IBA 02/2020
1	LectinsIBA 02/2020
1	Biological ProductsIBA 02/2020
1	Glycoproteins (Glycoprotein)IBA 02/2020
1	Leucine (L-Leucine)FDA Link 05/2018
1	RNA (Ribonucleic Acid)IBA 05/2018
1	Fulvestrant (Faslodex)FDA Link 12/2017
1	Estradiol (Delestrogen)FDA LinkGeneric 12/2017
1	Everolimus FDA Link 12/2017
1	Valosin Containing ProteinIBA 04/2017
1	Chalcone (Benzalacetophenone)IBA 04/2017
1	A Kinase Anchor ProteinsIBA 01/2017
1	Estrogen ReceptorsIBA 05/2015
1	Insulin-Like PeptidesIBA 05/2015
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 05/2015
1	Estrogen Receptor alphaIBA 01/2015
1	alpha KaryopherinsIBA 01/2015
1	GlycosyltransferasesIBA 02/2014
1	AcetylglucosamineIBA 02/2014
1	AcetylgalactosamineIBA 02/2014
1	Tumor Biomarkers (Tumor Markers)IBA 02/2014
1	Parathyroid Hormone-Related ProteinIBA 01/2014
1	Staphylococcal Protein A (Protein A)IBA 01/2014
1	protein KIBA 02/2013
1	DNA (Deoxyribonucleic Acid)IBA 05/2012
1	CaspasesIBA 07/2009
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 04/2009
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 04/2009
1	AntibodiesIBA 10/2008
1	MercuryIBA 06/2006
1	GoldIBA 06/2006
1	GliotoxinIBA 01/2006
1	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 01/2005
1	LeukotrienesIBA 10/2002

Therapy/Procedure

3	Therapeutics 09/2021 - 12/2017
2	Lasers (Laser) 02/2013 - 05/2012
1	Drug Therapy (Chemotherapy) 09/2021
1	Radiotherapy 09/2021